9BOT
Human mesotrypsin (PRSS3) unliganded and in autoinhibited (E*) conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Trypsin-3 | polymer | 224 | 24287.5 | 1 | UniProt (P35030) Pfam (PF00089) | Homo sapiens (human) | Brain trypsinogen,Mesotrypsinogen,Serine protease 3,Serine protease 4,Trypsin III,Trypsin IV |
| 2 | B, C (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | D (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | E (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 5 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | G (A) | water | water | 18.0 | 200 | Chemie (HOH) |
Sequence modifications
A: 16 - 246 (UniProt: P35030)
| PDB | External Database | Details |
|---|---|---|
| Ala 195 | Ser 257 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24287.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 383.3 | |
| All* | Total formula weight | 24670.8 |
