9BOQ

Human p97/VCP structure with a triazole inhibitor (NSC799462/dodecamer)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Transitional endoplasmic reticulum ATPase	polymer	806	89436.8	12	UniProt (P55072) Pfam (PF02359) Pfam (PF02933) Pfam (PF00004) Pfam (PF17862)	Homo sapiens (human)	TER ATPase,15S Mg(2+)-ATPase p97 subunit,Valosin-containing protein,VCP
2	BA, CA, EA, FA, HA... (F, G, H, I, A...)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	24	Chemie (ADP)
3	AA, DA, GA, JA, MA... (E, F, G, H, I...)	3-(2,6-difluoro-4-{[(4P)-5-{[(2S)-hexan-2-yl]sulfanyl}-4-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]methoxy}phenyl)prop-2-yn-1-yl (1-methylpiperidin-4-yl)carbamate	non-polymer		598.7	12	Chemie (XKM)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	1073241.8
Non-Polymers*	Number of molecules	36
	Total formula weight	17437.3
All*	Total formula weight	1090679.1

*Water molecules are not included.