9BOP
A broadly-neutralizing antibody against Ebolavirus glycoprotein that can potentiate the breadth and neutralization potency of other anti-glycoprotein antibodies
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, I, J (A, C, E) | 11883 heavy chain | polymer | 148 | 15837.8 | 3 | Oryctolagus cuniculus (rabbit) | ||
| 2 | B, K, L (B, D, F) | 11883 light chain | polymer | 140 | 14970.9 | 3 | Oryctolagus cuniculus (rabbit) | ||
| 3 | C, E (M, O) | 11886 heavy chain | polymer | 146 | 15855.0 | 2 | Oryctolagus cuniculus (rabbit) | ||
| 4 | D, F (N, P) | 11886 light chain | polymer | 141 | 15134.1 | 2 | Oryctolagus cuniculus (rabbit) | ||
| 5 | G, O, P (S, T, U) | Virion spike glycoprotein GP1 | polymer | 279 | 31256.1 | 3 | UniProt (A0A8G0KJC2) | Ebolavirus | |
| 6 | H, M, N (V, W, X) | Virion spike glycoprotein GP2 | polymer | 135 | 15206.2 | 3 | UniProt (A0A8G0KMX8) | Ebolavirus | |
| 7 | Q, R, S (G, H, I) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
| 8 | AA, BA, T, U, V... (U, S, T) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) |
Sequence modifications
S, T, U: 32 - 309 (UniProt: A0A8G0KJC2)
| PDB | External Database | Details |
|---|---|---|
| Arg 31 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 293791.6 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 2732.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1990.9 | |
| All* | Total formula weight | 298514.9 |
