9BNL
Cryo-EM structure of rhesus antibody 6070-a.01 in complex with HIV-1 Env trimer Q23.17 MD39
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, D (A, C, E) | Envelope glycoprotein Gp120 | polymer | 464 | 52382.4 | 3 | UniProt (O55774) | Human immunodeficiency virus 1 | Env polyprotein |
| 2 | B, E, F (B, F, G) | Envelope glycoprotein Gp41 | polymer | 142 | 16291.5 | 3 | UniProt (O55774) | Human immunodeficiency virus 1 | Env polyprotein |
| 3 | G (H) | 6070-a.01 heavy chain | polymer | 131 | 14704.4 | 1 | Macaca mulatta (Rhesus monkey) | ||
| 4 | H (L) | 6070-a.01 light chain | polymer | 107 | 11548.9 | 1 | Macaca mulatta (Rhesus monkey) | ||
| 5 | I (D) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 6 | AA, BA, CA, EA, GA... (a, b, c, e, g...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 26 | In PDB GlyTouCan (G42666HT) | |||
| 7 | DA, FA, JA, K, LA... (d, f, j, J, l...) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 11 | In PDB GlyTouCan (G15407YE) | |||
| 8 | HA (h) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 9 | UA (u) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G56014GC) | |||
| 10 | AB, BB, CB, DB, EB... (B, C, E, F, G...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 20 | Chemie (NAG) |
Sequence modifications
A, C, E: 33 - 505 (UniProt: O55774)
B, F, G: 520 - 661 (UniProt: O55774)
| PDB | External Database | Details |
|---|---|---|
| Glu 106 | Thr 105 | conflict |
| Ile 271 | Thr 263 | conflict |
| Val 304 | Arg 296 | conflict |
| Tyr 319 | Ala 309 | conflict |
| Ser 473 | Gly 463 | conflict |
| Cys 501 | Ala 491 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 533 | Thr 523 | conflict |
| Asn 543 | Gln 533 | conflict |
| His 570 | Val 560 | conflict |
| His 585 | Arg 575 | conflict |
| Cys 605 | Thr 595 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 232275.0 | |
| Branched | Number of molecules | 40 |
| Total formula weight | 20218.9 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 4424.2 | |
| All* | Total formula weight | 256918.0 |
