9BN9
Crystal Structure of UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from E. coli in complex with UMA and two inhibitor A19 molecules
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | UDP-N-acetylmuramoylalanine--D-glutamate ligase | polymer | 445 | 47949.4 | 1 | UniProt (P14900) Pfam (PF21799) Pfam (PF08245) Pfam (PF02875) | Escherichia coli K-12 | D-glutamic acid-adding enzyme,UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase |
| 2 | B (A) | URIDINE-5'-DIPHOSPHATE-N-ACETYLMURAMOYL-L-ALANINE | non-polymer | 750.5 | 1 | Chemie (UMA) | |||
| 3 | C, D (A) | N-(4-{[(4S)-3-amino[1,2,4]triazolo[4,3-b]pyridazin-6-yl]sulfanyl}phenyl)acetamide | non-polymer | 300.3 | 2 | Chemie (A1AQS) | |||
| 4 | E, F, G, H, I... (A) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 5 | K, L (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | M (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | N (A) | water | water | 18.0 | 526 | Chemie (HOH) |
Sequence modifications
A: 0 - 437 (UniProt: P14900)
| PDB | External Database | Details |
|---|---|---|
| Gly 438 | - | expression tag |
| His 439 | - | expression tag |
| His 440 | - | expression tag |
| His 441 | - | expression tag |
| His 442 | - | expression tag |
| His 443 | - | expression tag |
| His 444 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 47949.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2090.6 | |
| All* | Total formula weight | 50039.9 |
