9BN8
Crystal Structure of UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from E. coli in complex with UMA and inhibitor A19
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | UDP-N-acetylmuramoylalanine--D-glutamate ligase | polymer | 445 | 47906.4 | 1 | UniProt (P14900) Pfam (PF21799) Pfam (PF08245) Pfam (PF02875) In PDB | Escherichia coli K-12 | |
| 2 | A | URIDINE-5'-DIPHOSPHATE-N-ACETYLMURAMOYL-L-ALANINE | non-polymer | 750.5 | 1 | Chemie (UMA) | |||
| 3 | A | N-(4-{[(4S)-3-amino[1,2,4]triazolo[4,3-b]pyridazin-6-yl]sulfanyl}phenyl)acetamide | non-polymer | 300.3 | 1 | Chemie (A1AQS) | |||
| 4 | A | SULFATE ION | non-polymer | 96.1 | 11 | Chemie (SO4) | |||
| 5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | water | water | 18.0 | 504 | Chemie (HOH) |
Sequence modifications
A: 0 - 437 (UniProt: P14900)
| PDB | External Database | Details |
|---|---|---|
| Gly 438 | - | expression tag |
| His 439 | - | expression tag |
| His 440 | - | expression tag |
| His 441 | - | expression tag |
| His 442 | - | expression tag |
| His 443 | - | expression tag |
| His 444 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 47906.4 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2199.6 | |
| All* | Total formula weight | 50106.0 |
