9BLH
Crystal structure of calcium/calmodulin-dependent protein kinase type II subunit delta complexed with ribociclib
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | Calcium/calmodulin-dependent protein kinase type II subunit delta | polymer | 300 | 34182.4 | 2 | UniProt (Q13557) Pfam (PF00069) | Homo sapiens (human) | CaM kinase II subunit delta,CaMK-II subunit delta |
2 | C, D (A, B) | 7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide | non-polymer | 434.5 | 2 | Chemie (6ZZ) | |||
3 | E, F (A, B) | water | water | 18.0 | 73 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 68364.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 869.1 | |
All* | Total formula weight | 69233.8 |