9BJ9
Human CRL-2 ZYG11B binding to human NLRP1 Gly/N degron
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein zyg-11 homolog B | polymer | 748 | 84463.3 | 1 | UniProt (Q9C0D3) | Homo sapiens (human) | |
| 2 | B (B) | Elongin-B | polymer | 118 | 13147.8 | 1 | UniProt (Q15370) | Homo sapiens (human) | EloB,Elongin 18 kDa subunit,RNA polymerase II transcription factor SIII subunit B,SIII p18,Transcription elongation factor B polypeptide 2 |
| 3 | C (C) | Elongin-C | polymer | 96 | 10843.4 | 1 | UniProt (Q15369) | Homo sapiens (human) | EloC, Elongin 15 kDa subunit, RNA polymerase II transcription factor SIII subunit C, SIII p15, Transcription elongation factor B polypeptide 1 |
| 4 | D (D) | Cullin-2 | polymer | 779 | 90428.5 | 1 | UniProt (Q13617) | Homo sapiens (human) | CUL-2 |
| 5 | E (P) | Peptide from NACHT, LRR and PYD domains-containing protein 1, N-terminus | polymer | 21 | 2124.5 | 1 | UniProt (Q9C000) | Homo sapiens (human) | NLRP1-NT |
| 6 | F (R) | E3 ubiquitin-protein ligase RBX1 | polymer | 108 | 12290.0 | 1 | UniProt (P62877) | Homo sapiens (human) | E3 ubiquitin-protein transferase RBX1,Protein ZYP,RING finger protein 75,RING-box protein 1,Rbx1,Regulator of cullins 1,ROC1 |
| 7 | G, H, I (R) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) |
Sequence modifications
A: 2 - 744 (UniProt: Q9C0D3)
D: 1 - 745 (UniProt: Q13617)
P: 1 - 9 (UniProt: Q9C000)
| PDB | External Database | Details |
|---|---|---|
| Ser -3 | - | expression tag |
| His -2 | - | expression tag |
| Met -1 | - | expression tag |
| Val 0 | - | expression tag |
| Asp 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 746 | - | expression tag |
| Glu 747 | - | expression tag |
| Gly 748 | - | expression tag |
| Gly 749 | - | expression tag |
| Gly 750 | - | expression tag |
| Gly 751 | - | expression tag |
| Trp 752 | - | expression tag |
| Ser 753 | - | expression tag |
| His 754 | - | expression tag |
| Pro 755 | - | expression tag |
| Gln 756 | - | expression tag |
| Phe 757 | - | expression tag |
| Glu 758 | - | expression tag |
| Lys 759 | - | expression tag |
| Gly 760 | - | expression tag |
| Gly 761 | - | expression tag |
| Gly 762 | - | expression tag |
| Ser 763 | - | expression tag |
| Gly 764 | - | expression tag |
| Gly 765 | - | expression tag |
| Gly 766 | - | expression tag |
| Ser 767 | - | expression tag |
| Gly 768 | - | expression tag |
| Gly 769 | - | expression tag |
| Gly 770 | - | expression tag |
| Ser 771 | - | expression tag |
| Trp 772 | - | expression tag |
| Ser 773 | - | expression tag |
| His 774 | - | expression tag |
| Pro 775 | - | expression tag |
| Gln 776 | - | expression tag |
| Phe 777 | - | expression tag |
| Glu 778 | - | expression tag |
| Lys 779 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Unk 10 | - | cloning artifact |
| Unk 11 | - | cloning artifact |
| Unk 12 | - | cloning artifact |
| Unk 13 | - | cloning artifact |
| Unk 14 | - | cloning artifact |
| Unk 15 | - | cloning artifact |
| Unk 16 | - | cloning artifact |
| Unk 17 | - | cloning artifact |
| Unk 18 | - | cloning artifact |
| Unk 19 | - | cloning artifact |
| Unk 20 | - | cloning artifact |
| Unk 21 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 213297.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 196.2 | |
| All* | Total formula weight | 213493.7 |
