9BIM

Cryo-EM structure of human CHT1 in the HC-3 bound outward-facing state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	High affinity choline transporter 1	polymer	614	66526.6	1	UniProt (Q9GZV3) Pfam (PF00474)	Homo sapiens (human)	hCHT1,Hemicholinium-3-sensitive choline transporter,CHT,Solute carrier family 5 member 7
2	B (A)	(2S,2'S)-2,2'-biphenyl-4,4'-diylbis(2-hydroxy-4,4-dimethylmorpholin-4-ium)	non-polymer		414.5	1	Chemie (HC6)

Sequence modifications

A: 1 - 580 (UniProt: Q9GZV3)

PDB	External Database	Details
Ala 581	-	expression tag
Ala 582	-	expression tag
Ala 583	-	expression tag
Gly 584	-	expression tag
Gly 585	-	expression tag
Ser 586	-	expression tag
Trp 587	-	expression tag
Ser 588	-	expression tag
His 589	-	expression tag
Pro 590	-	expression tag
Gln 591	-	expression tag
Phe 592	-	expression tag
Glu 593	-	expression tag
Lys 594	-	expression tag
Gly 595	-	expression tag
Gly 596	-	expression tag
Gly 597	-	expression tag
Ser 598	-	expression tag
Gly 599	-	expression tag
Gly 600	-	expression tag
Gly 601	-	expression tag
Ser 602	-	expression tag
Gly 603	-	expression tag
Gly 604	-	expression tag
Ser 605	-	expression tag
Ala 606	-	expression tag
Trp 607	-	expression tag
Ser 608	-	expression tag
His 609	-	expression tag
Pro 610	-	expression tag
Gln 611	-	expression tag
Phe 612	-	expression tag
Glu 613	-	expression tag
Lys 614	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	66526.6
Non-Polymers*	Number of molecules	1
	Total formula weight	414.5
All*	Total formula weight	66941.2

*Water molecules are not included.