9BI6
Human proton sensing receptor GPR68 in complex with miniGsq
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | miniGsq | polymer | 229 | 26451.0 | 1 | synthetic construct | ||
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 370 | 40786.6 | 1 | UniProt (P62873) Pfam (PF00400) | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 68 | 7563.8 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 4 | D (N) | Nb35 | polymer | 142 | 15398.1 | 1 | Lama glama | ||
| 5 | E (R) | Ovarian cancer G-protein coupled receptor 1 | polymer | 376 | 42372.7 | 1 | UniProt (Q15743) Pfam (PF00001) | Homo sapiens (human) | OGR-1,G-protein coupled receptor 68,GPR12A,Sphingosylphosphorylcholine receptor |
| 6 | F (R) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) |
Sequence modifications
B: 2 - 340 (UniProt: P62873)
R: 1 - 365 (UniProt: Q15743)
| PDB | External Database | Details |
|---|---|---|
| Met -29 | - | expression tag |
| His -28 | - | expression tag |
| His -27 | - | expression tag |
| His -26 | - | expression tag |
| His -25 | - | expression tag |
| His -24 | - | expression tag |
| His -23 | - | expression tag |
| Leu -22 | - | expression tag |
| Glu -21 | - | expression tag |
| Val -20 | - | expression tag |
| Leu -19 | - | expression tag |
| Phe -18 | - | expression tag |
| Gln -17 | - | expression tag |
| Gly -16 | - | expression tag |
| Pro -15 | - | expression tag |
| Glu -14 | - | expression tag |
| Asp -13 | - | expression tag |
| Gln -12 | - | expression tag |
| Val -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Pro -9 | - | expression tag |
| Arg -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Ile -6 | - | expression tag |
| Asp -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Lys -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asp -10 | - | expression tag |
| Tyr -9 | - | expression tag |
| Lys -8 | - | expression tag |
| Asp -7 | - | expression tag |
| Asp -6 | - | expression tag |
| Asp -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Ile -1 | - | expression tag |
| Asp 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 132572.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 486.7 | |
| All* | Total formula weight | 133058.8 |
