9BFQ

Cryo-EM structure of Sevenless in complex with Bride of Sevenless

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Protein sevenless	polymer	2002	225292.9	1	UniProt (P13368) Pfam (PF00041)	Drosophila melanogaster (fruit fly)
2	B (B)	Protein bride of sevenless	polymer	505	57278.7	1	UniProt (P22815)	Drosophila melanogaster (fruit fly)
3	C, D, E, F, G (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)

Sequence modifications

A: 123 - 2110 (UniProt: P13368)

PDB	External Database	Details
-	Arg 2038	deletion
-	Arg 2039	deletion
-	Arg 2040	deletion
-	Arg 2041	deletion
-	Arg 2042	deletion
-	Arg 2043	deletion
-	Arg 2044	deletion
-	Arg 2045	deletion
-	Arg 2046	deletion
His 2111	-	expression tag
His 2112	-	expression tag
His 2113	-	expression tag
His 2114	-	expression tag
His 2115	-	expression tag
His 2116	-	expression tag
Trp 2117	-	expression tag
Ser 2118	-	expression tag
His 2119	-	expression tag
Pro 2120	-	expression tag
Gln 2121	-	expression tag
Phe 2122	-	expression tag
Glu 2123	-	expression tag
Lys 2124	-	expression tag

B: 32 - 530 (UniProt: P22815)

PDB	External Database	Details
His 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	282571.6
Non-Polymers*	Number of molecules	5
	Total formula weight	1106.0
All*	Total formula weight	283677.7

*Water molecules are not included.