9BFC
Cryo-EM structure of importin alpha-1/beta bound to FG repeats
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (F) | PHE-GLY-ALA | polymer | 3 | 293.3 | 1 | Saccharomyces cerevisiae | ||
| 2 | B (H) | Importin subunit beta-1 | polymer | 876 | 97323.9 | 1 | UniProt (Q14974) Pfam (PF03810) Pfam (PF00514) Pfam (PF25574) | Homo sapiens (human) | Importin-90,Karyopherin subunit beta-1,Nuclear factor p97,Pore targeting complex 97 kDa subunit,PTAC97 |
| 3 | C (I) | Importin subunit alpha-1 | polymer | 53 | 6356.4 | 1 | UniProt (P52292) Pfam (PF01749) | Homo sapiens (human) | Karyopherin subunit alpha-2,RAG cohort protein 1,SRP1-alpha |
| 4 | D (J) | LYS-PRO-ALA-PHE-SER-PHE-GLY | polymer | 7 | 753.9 | 1 | Saccharomyces cerevisiae | ||
| 5 | E (C) | ALA-PHE-SER-PHE | polymer | 4 | 470.5 | 1 | Saccharomyces cerevisiae | ||
| 6 | F, H (H) | PHENYLALANINE | non-polymer | 165.2 | 2 | Chemie (PHE) | |||
| 7 | G (H) | GLYCINE | non-polymer | 75.1 | 1 | Chemie (GLY) |
Sequence modifications
H: 1 - 876 (UniProt: Q14974)
| PDB | External Database | Details |
|---|---|---|
| His 97 | Gln 97 | conflict |
| Arg 863 | Thr 863 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 105198.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 405.4 | |
| All* | Total formula weight | 105603.4 |
