9BEX
X-ray crystallography structural model of the immunoglobulin G1 (IgG1) Fc D270C K326C variant
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (AAA, BBB) | Immunoglobulin gamma-1 heavy chain | polymer | 232 | 26088.6 | 2 | UniProt (P0DOX5) Pfam (PF07654) | Homo sapiens (human) | Immunoglobulin gamma-1 heavy chain NIE |
| 2 | C, D (AaA, BaB) | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1625.5 | 2 | In PDB GlyTouCan (G33244HE) | |||
| 3 | E (AAA) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 4 | F, G (AAA, BBB) | water | water | 18.0 | 90 | Chemie (HOH) |
Sequence modifications
AAA, BBB: 216 - 447 (UniProt: P0DOX5)
| PDB | External Database | Details |
|---|---|---|
| Cys 270 | Asp 272 | engineered mutation |
| Cys 326 | Lys 328 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52177.2 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 3251.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 106.1 | |
| All* | Total formula weight | 55534.3 |
