9BDF
Influenza A virus Hemagglutinin H3/Darwin/6/2021 in complex with Fab ADI-85666
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F, G (A, G, H) | Hemagglutinin | polymer | 514 | 57485.4 | 3 | UniProt (A0A8F5JT24) | Influenza A virus | |
| 2 | B, C, E (B, C, E) | ADI-85666 Fab heavy chain | polymer | 240 | 25579.8 | 3 | Homo sapiens | ||
| 3 | D, H, I (D, I, J) | ADI-85666 Fab light chain | polymer | 214 | 23403.0 | 3 | Homo sapiens | ||
| 4 | J, M, R (F, M, R) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G81315DD) | |||
| 5 | K, N, O, P, Q (K, N, O, P, Q) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 5 | In PDB GlyTouCan (G42666HT) | |||
| 6 | L (L) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 7 | AA, BA, CA, DA, EA... (G, H, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 16 | Chemie (NAG) |
Sequence modifications
A, G, H: 1 - 505 (UniProt: A0A8F5JT24)
| PDB | External Database | Details |
|---|---|---|
| Asn 31 | Asp 47 | conflict |
| Gly 53 | Asp 69 | conflict |
| Trp 355 | His 371 | conflict |
| Ile 380 | Lys 396 | conflict |
| Ile 432 | Glu 448 | conflict |
| Ala 505 | Val 521 | conflict |
| Gly 506 | - | expression tag |
| Ser 507 | - | expression tag |
| Ser 508 | - | expression tag |
| Leu 509 | - | expression tag |
| Glu 510 | - | expression tag |
| Val 511 | - | expression tag |
| Leu 512 | - | expression tag |
| Phe 513 | - | expression tag |
| Gln 514 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 319404.6 | |
| Branched | Number of molecules | 9 |
| Total formula weight | 4954.6 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3539.3 | |
| All* | Total formula weight | 327898.5 |
