9BCQ

Extracellular domain of GC-A bound to ANP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Atrial natriuretic peptide receptor 1	polymer	1040	116770.9	2	UniProt (P16066) Pfam (PF01094) Pfam (PF07714) Pfam (PF00211)	Homo sapiens (human)	Atrial natriuretic peptide receptor type A,ANP-A,ANPR-A,NPR-A,Guanylate cyclase A,GC-A
2	C (C)	Atrial natriuretic peptide	polymer	28	3087.5	1	UniProt (P01160) Pfam (PF00212)	Homo sapiens (human)	ANP,Alpha-atrial natriuretic peptide,Alpha-hANP,Atrial natriuretic factor,ANF,CDD-ANF,CDD-ANP (99-126),Cardionatrin,Pro atrial natriuretic factor 99-126,proANF 99-126
3	D, E, F (D, E, F)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
4	G (G)	alpha-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G66019PC)
5	H, I (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
6	J (B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

A, B: 0 - 1029 (UniProt: P16066)

PDB	External Database	Details
Asp -10	-	expression tag
Tyr -9	-	expression tag
Lys -8	-	expression tag
Asp -7	-	expression tag
Asp -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Lys -3	-	expression tag
Ala -2	-	expression tag
Ala -1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	236629.2
Branched	Number of molecules	4
	Total formula weight	1859.7
Non-Polymers*	Number of molecules	3
	Total formula weight	292.1
All*	Total formula weight	238781.1

*Water molecules are not included.