9BCG
Myeloid cell leukemia-1 (Mcl-1) complexed with compound
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 516 | 57168.7 | 1 | UniProt (P0AEX9) UniProt (Q07820) Pfam (PF01547) Pfam (PF00452) In PDB | Homo sapiens (human) | MMBP,Maltodextrin-binding protein,Maltose-binding protein,MBP,Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT |
| 2 | B | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900001) GlyTouCan (G07411ON) | |||
| 3 | A | 7-[(4R,5S,6P)-7-chloro-10-[3-(4-chloro-3,5-dimethylphenoxy)propyl]-4-methyl-1-oxo-6-(1,3,5-trimethyl-1H-pyrazol-4-yl)-3,4-dihydropyrazino[1,2-a]indol-2(1H)-yl]-4,5-dimethoxy-1-methyl-1H-indole-2-carboxylic acid | non-polymer | 772.7 | 1 | Chemie (A1ALT) | |||
| 4 | water | water | 18.0 | 591 | Chemie (HOH) |
Sequence modifications
A: -196 - 170 (UniProt: P0AEX9)
A: 173 - 320 (UniProt: Q07820)
| PDB | External Database | Details |
|---|---|---|
| - | Gly 200 | deletion |
| Gly 171 | - | linker |
| Ser 172 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ala 194 | Lys 194 | conflict |
| Ala 197 | Lys 197 | conflict |
| Ala 201 | Arg 201 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 57168.7 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 772.7 | |
| All* | Total formula weight | 58283.7 |
