9BBK
SARS-CoV-2 full-length spike protein with His1271Lys substitution in the coatomer binding motif, 2RBD-up conformation (SPIKE-KxK)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Spike glycoprotein | polymer | 1312 | 144843.0 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 2019-nCoV COVID-19 virus) | S glycoprotein,E2,Peplomer protein |
| 2 | D, EA, FA, L, M... (D, f, g, L, M...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 9 | In PDB GlyTouCan (G42666HT) | |||
| 3 | DA, E, F, G, I... (e, E, F, G, I...) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 11 | In PDB GlyTouCan (G15407YE) | |||
| 4 | BA, H (c, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 5 | O, P (P, Q) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G22573RC) | |||
| 6 | Q (R) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 7 | AA, R, Z (b, S, a) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G81315DD) | |||
| 8 | CA (d) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | In PDB GlyTouCan (G42466VF) | |||
| 9 | AB, GA, HA, IA, JA... (C, A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 21 | Chemie (NAG) |
Sequence modifications
A, B, C: -38 - 1273 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Ser -20 | - | insertion |
| Ala -19 | - | insertion |
| Trp -18 | - | insertion |
| Ser -17 | - | insertion |
| His -16 | - | insertion |
| Pro -15 | - | insertion |
| Gln -14 | - | insertion |
| Phe -13 | - | insertion |
| Glu -12 | - | insertion |
| Lys -11 | - | insertion |
| Gly -10 | - | insertion |
| Gly -9 | - | insertion |
| Gly -8 | - | insertion |
| Ser -7 | - | insertion |
| Gly -6 | - | insertion |
| Gly -5 | - | insertion |
| Gly -4 | - | insertion |
| Ser -3 | - | insertion |
| Gly -2 | - | insertion |
| Gly -1 | - | insertion |
| Ser 0 | - | insertion |
| Ser 1 | - | insertion |
| Ala 2 | - | insertion |
| Trp 3 | - | insertion |
| Ser 4 | - | insertion |
| His 5 | - | insertion |
| Pro 6 | - | insertion |
| Gln 7 | - | insertion |
| Phe 8 | - | insertion |
| Glu 9 | - | insertion |
| Lys 10 | - | insertion |
| Ser 11 | - | insertion |
| Ala 12 | - | insertion |
| Leu 13 | - | insertion |
| Val 14 | - | insertion |
| Pro 15 | - | insertion |
| Arg 16 | - | insertion |
| Gly 17 | - | insertion |
| Ser 18 | - | insertion |
| Gly 614 | Asp 614 | variant |
| Gly 682 | Arg 682 | engineered mutation |
| Ser 683 | Arg 683 | engineered mutation |
| Ser 685 | Arg 685 | engineered mutation |
| Pro 986 | Lys 986 | engineered mutation |
| Pro 987 | Val 987 | engineered mutation |
| Lys 1271 | His 1271 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 434529.1 | |
| Branched | Number of molecules | 29 |
| Total formula weight | 16783.6 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 4645.4 | |
| All* | Total formula weight | 455958.1 |
