9BAW
Cryo-EM structure of human importin beta-Ran-GTP heterodimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Importin subunit beta-1 | polymer | 876 | 97323.9 | 1 | UniProt (Q14974) Pfam (PF03810) Pfam (PF00514) Pfam (PF25574) | Homo sapiens (human) | Importin-90,Karyopherin subunit beta-1,Nuclear factor p97,Pore targeting complex 97 kDa subunit,PTAC97 |
| 2 | B (B) | GTP-binding nuclear protein Ran | polymer | 170 | 19539.7 | 1 | UniProt (P62826) Pfam (PF00071) | Homo sapiens (human) | Androgen receptor-associated protein 24,GTPase Ran,Ras-like protein TC4,Ras-related nuclear protein |
| 3 | C (B) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 4 | D (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence modifications
A: 1 - 876 (UniProt: Q14974)
B: 9 - 178 (UniProt: P62826)
| PDB | External Database | Details |
|---|---|---|
| His 97 | Gln 97 | conflict |
| Arg 863 | Thr 863 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 177 | Val 177 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 116863.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 547.5 | |
| All* | Total formula weight | 117411.1 |
