9BAJ

Crystal structure of GDP-bound human K-RAS in a covalent complex with aryl sulfonyl fluoride compounds.

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	Isoform 2B of GTPase KRas	polymer	169	19255.7	2	UniProt (P01116) Pfam (PF00071)	Homo sapiens (human)	K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
2	B (B)	Isoform 2B of GTPase KRas	polymer	169	19271.7	1	UniProt (P01116) Pfam (PF00071)	Homo sapiens (human)	K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
3	C (C)	Isoform 2B of GTPase KRas	polymer	169	19271.7	1	UniProt (P01116) Pfam (PF00071)	Homo sapiens (human)	K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
4	E, H, K, N (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
5	F, I, L, O (A, B, C, D)	3-(dioxo-lambda~6~-sulfanyl)-N-phenylbenzene-1-sulfonamide	non-polymer		297.4	4	Chemie (A1AK8)
6	G, J, M, P (A, B, C, D)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	4	Chemie (GDP)
7	Q, R, S, T (A, B, C, D)	water	water		18.0	773	Chemie (HOH)

Sequence modifications

A, D: 1 - 169 (UniProt: P01116)

PDB	External Database	Details
Ser 118	Cys 118	engineered mutation

B: 1 - 169 (UniProt: P01116)

PDB	External Database	Details
Ser 118	Cys 118	engineered mutation

C: 1 - 169 (UniProt: P01116)

PDB	External Database	Details
Ser 118	Cys 118	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	77054.8
Non-Polymers*	Number of molecules	12
	Total formula weight	3059.4
All*	Total formula weight	80114.2

*Water molecules are not included.