9B9J

Integrin alpha-5 beta-1 in complex with BIIG2 Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Integrin alpha-5 light chain	polymer	995	108693.7	1	UniProt (P08648) Pfam (PF01839) Pfam (PF08441) Pfam (PF20805) Pfam (PF20806)	Homo sapiens (human)
2	B (B)	Integrin beta-1	polymer	728	80653.8	1	UniProt (P05556) Pfam (PF07965) Pfam (PF17205) Pfam (PF00362) Pfam (PF18372) Pfam (PF07974)	Homo sapiens (human)	Fibronectin receptor subunit beta,Glycoprotein IIa,GPIIA,VLA-4 subunit beta
3	C (H)	BIIG2 Fab Heavy Chain	polymer	217	23400.1	1		Rattus norvegicus (Norway rat)
4	D (L)	BIIG2 Fab Light Chain	polymer	214	23421.0	1		Rattus norvegicus (Norway rat)
5	E, F, G, H, M (C, D, E, F, M)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	5	In PDB GlyTouCan (G15407YE)
6	I (G)	alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1073.0	1	In PDB GlyTouCan (G09724ZC)
7	J, K, L (I, J, K)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
8	N (N)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
9	O, P, Q, R, S... (A, B)	CALCIUM ION	non-polymer		40.1	7	Chemie (CA)
10	V (B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	236168.7
Branched	Number of molecules	10
	Total formula weight	6027.6
Non-Polymers*	Number of molecules	8
	Total formula weight	501.8
All*	Total formula weight	242698.0

*Water molecules are not included.