9B9F
Zebrafish Betaglycan Orphan Domain (zfBGo) in complex with TGF-B3 and extracellular domains of TGFBRI and TGFBRII
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F (A, F) | Transforming growth factor beta-3 | polymer | 112 | 12734.5 | 2 | UniProt (P10600) Pfam (PF00019) | Homo sapiens (human) | TGF-beta-3 |
| 2 | B, G (B, G) | Transforming growth factor beta-3 triple mutant | polymer | 112 | 12586.2 | 2 | UniProt (P10600) Pfam (PF00019) | Homo sapiens (human) | TGF-beta-3 |
| 3 | C, H (C, H) | Transforming growth factor beta receptor type-1 | polymer | 87 | 9474.8 | 2 | UniProt (P36897) Pfam (PF01064) | Homo sapiens (human) | TGFR-1,Activin A receptor type II-like protein kinase of 53kD,Activin receptor-like kinase 5,ALK-5,ALK5,Serine/threonine-protein kinase receptor R4,SKR4,TGF-beta type I receptor,Transforming growth factor-beta receptor type I,TGF-beta receptor type I,TbetaR-I |
| 4 | D, I (D, I) | Transforming growth factor beta receptor type-2 | polymer | 113 | 12926.8 | 2 | UniProt (P37173) Pfam (PF08917) | Homo sapiens (human) | |
| 5 | E, J (E, J) | Transforming growth factor beta receptor type-3 | polymer | 338 | 37727.0 | 2 | UniProt (A0A0H3UK16) UniProt (by SIFTS) (E7FDB6) | Danio rerio (zebrafish) | Transforming growth factor beta receptor type 3 precursor |
Sequence modifications
B, G: 301 - 412 (UniProt: P10600)
C, H: 29 - 113 (UniProt: P36897)
D, I: 42 - 153 (UniProt: P37173)
E, J: 29 - 359 (UniProt: A0A0H3UK16)
| PDB | External Database | Details |
|---|---|---|
| Glu 325 | Arg 325 | engineered mutation |
| Ala 390 | Tyr 390 | engineered mutation |
| Glu 394 | Arg 394 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 27 | - | expression tag |
| Ser 28 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 41 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Gly 28 | - | expression tag |
| Gly 150 | Cys 150 | engineered mutation |
| Gly 277 | Cys 277 | engineered mutation |
| His 360 | - | expression tag |
| His 361 | - | expression tag |
| His 362 | - | expression tag |
| His 363 | - | expression tag |
| His 364 | - | expression tag |
| His 365 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 170898.8 | |
| All* | Total formula weight | 170898.8 |
