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9B90

Cryo-EM structure of the human TRPM4 channel in complex with calcium and ATP at 37 degrees Celsius

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DTransient receptor potential cation channel subfamily M member 4polymer1214134456.54UniProt (Q8TD43)
Pfam (PF18139)
Pfam (PF00520)
In PDB
Homo sapiens (human)hTRPM4,Calcium-activated non-selective cation channel 1,Long transient receptor potential channel 4,LTrpC4,Melastatin-4
2A, B, C, DCALCIUM IONnon-polymer40.18Chemie (CA)
3A, B, C, DADENOSINE-5'-TRIPHOSPHATEnon-polymer507.24Chemie (ATP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight537825.9
Non-Polymers*Number of molecules12
Total formula weight2349.3
All*Total formula weight540175.3
*Water molecules are not included.

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PDB entries from 2024-07-31

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