9B8U

Crystal structure of CRX-Ret4 oligonucleotide complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Cone-rod homeobox protein	polymer	81	9780.1	4	UniProt (O43186) In PDB	Homo sapiens (human)
2	E, G	DNA (5'-D(P*CP*AP*GP*GP*AP*GP*CP*TP*TP*AP*GP*GP*AP*GP*GP*GP*GP*GP*AP*G)-3')	polymer	21	6618.3	2		Homo sapiens
3	F, H	DNA (5'-D(P*CP*TP*CP*CP*CP*CP*CP*TP*CP*CP*TP*AP*AP*GP*CP*TP*CP*CP*TP*G)-3')	polymer	21	6231.0	2		Homo sapiens
4	A, E	CACODYLATE ION	non-polymer		137.0	2	Chemie (CAC)
5	A	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	1	Chemie (MPD)
6	B, F, H	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
7	E, F, H	POTASSIUM ION	non-polymer		39.1	3	Chemie (K)
8	G	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
9		water	water		18.0	55	Chemie (HOH)

Sequence modifications

A, B, C, D: 31 - 107 (UniProt: O43186)

PDB	External Database	Details
Gly 27	-	expression tag
Ala 28	-	expression tag
Met 29	-	expression tag
Asp 30	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	64818.8
Non-Polymers*	Number of molecules	12
	Total formula weight	923.8
All*	Total formula weight	65742.6

*Water molecules are not included.