9B82

Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody COVA2-15

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, G, J, M... (A, C, B, D, E...)	Spike protein S1	polymer	205	23104.9	6	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2
2	B, E, H, K, N... (H, I, K, N, P...)	COVA2-15 antibody heavy chain	polymer	232	24360.2	6		Homo sapiens (human)
3	C, F, I, L, O... (L, G, J, M, O...)	COVA2-15 antibody light chain	polymer	219	24192.9	6		Homo sapiens (human)
4	S, T, U, V, W... (A, C, B, D, E...)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)

Sequence modifications

A, C, B, D, E, F: 333 - 530 (UniProt: P0DTC2)

PDB	External Database	Details
Gly 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	18
	Total formula weight	429947.6
Non-Polymers*	Number of molecules	6
	Total formula weight	1327.2
All*	Total formula weight	431274.9

*Water molecules are not included.