9B7G
Cryo-EM structure of antibody TJ5-13 bound to H3 COBRA NG2 hemagglutinin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G (A, B, C) | Hemagglutinin | polymer | 557 | 62717.1 | 3 | UniProt (A0A2P1ADT1) Pfam (PF00509) | Influenza A virus | |
| 2 | B, E, H (H, J, Q) | TJ5-13 Fab heavy chain | polymer | 242 | 25796.8 | 3 | Homo sapiens (human) | ||
| 3 | C, F, I (L, K, P) | TJ5-13 Fab light chain | polymer | 216 | 22762.1 | 3 | Homo sapiens (human) | ||
| 4 | J, N, R (D, I, R) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 3 | In PDB GlyTouCan (G86851RC) | |||
| 5 | K, O, S (E, M, S) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 3 | In PDB GlyTouCan (G21290RB) | |||
| 6 | L, P, T (F, N, T) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G81315DD) | |||
| 7 | M, Q, U (G, O, U) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 8 | AA, BA, CA, DA, V... (B, C, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) |
Sequence modifications
A, B, C: 1 - 506 (UniProt: A0A2P1ADT1)
| PDB | External Database | Details |
|---|---|---|
| Gly 142 | Arg 158 | conflict |
| Ser 144 | Lys 160 | conflict |
| Gln 311 | His 327 | conflict |
| Gly 507 | - | expression tag |
| Tyr 508 | - | expression tag |
| Ile 509 | - | expression tag |
| Pro 510 | - | expression tag |
| Glu 511 | - | expression tag |
| Ala 512 | - | expression tag |
| Pro 513 | - | expression tag |
| Arg 514 | - | expression tag |
| Asp 515 | - | expression tag |
| Gly 516 | - | expression tag |
| Gln 517 | - | expression tag |
| Ala 518 | - | expression tag |
| Tyr 519 | - | expression tag |
| Val 520 | - | expression tag |
| Arg 521 | - | expression tag |
| Lys 522 | - | expression tag |
| Asp 523 | - | expression tag |
| Gly 524 | - | expression tag |
| Glu 525 | - | expression tag |
| Trp 526 | - | expression tag |
| Val 527 | - | expression tag |
| Leu 528 | - | expression tag |
| Leu 529 | - | expression tag |
| Ser 530 | - | expression tag |
| Thr 531 | - | expression tag |
| Phe 532 | - | expression tag |
| Leu 533 | - | expression tag |
| Gly 534 | - | expression tag |
| Ser 535 | - | expression tag |
| Gly 536 | - | expression tag |
| Leu 537 | - | expression tag |
| Asn 538 | - | expression tag |
| Asp 539 | - | expression tag |
| Ile 540 | - | expression tag |
| Phe 541 | - | expression tag |
| Glu 542 | - | expression tag |
| Ala 543 | - | expression tag |
| Gln 544 | - | expression tag |
| Lys 545 | - | expression tag |
| Ile 546 | - | expression tag |
| Glu 547 | - | expression tag |
| Trp 548 | - | expression tag |
| His 549 | - | expression tag |
| Glu 550 | - | expression tag |
| Gly 551 | - | expression tag |
| His 552 | - | expression tag |
| His 553 | - | expression tag |
| His 554 | - | expression tag |
| His 555 | - | expression tag |
| His 556 | - | expression tag |
| His 557 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 333827.9 | |
| Branched | Number of molecules | 12 |
| Total formula weight | 6332.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1990.9 | |
| All* | Total formula weight | 342151.7 |
