9B6C

Human asparagine synthetase Arg-142 to Ile-142 (R142I) variant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Asparagine synthetase [glutamine-hydrolyzing]	polymer	579	66672.1	2	UniProt (P08243) Pfam (PF13537) Pfam (PF00733)	Homo sapiens (human)	Cell cycle control protein TS11,Glutamine-dependent asparagine synthetase

Sequence modifications

A, B: 1 - 560 (UniProt: P08243)

PDB	External Database	Details
Ile 142	Arg 143	engineered mutation
Ala 561	-	expression tag
Gly 562	-	expression tag
Glu 563	-	expression tag
Asn 564	-	expression tag
Leu 565	-	expression tag
Tyr 566	-	expression tag
Phe 567	-	expression tag
Gln 568	-	expression tag
Ser 569	-	expression tag
His 570	-	expression tag
His 571	-	expression tag
His 572	-	expression tag
His 573	-	expression tag
His 574	-	expression tag
His 575	-	expression tag
His 576	-	expression tag
His 577	-	expression tag
His 578	-	expression tag
His 579	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	133344.2
All*	Total formula weight	133344.2

*Water molecules are not included.