9B4Y
Cryo-EM structure of importin alpha-1/beta bound to TDP-43
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Importin subunit beta-1 | polymer | 876 | 97323.9 | 1 | UniProt (Q14974) Pfam (PF03810) Pfam (PF00514) | Homo sapiens (human) | Importin-90,Karyopherin subunit beta-1,Nuclear factor p97,Pore targeting complex 97 kDa subunit,PTAC97 |
| 2 | B (B) | Importin subunit alpha-1 | polymer | 43 | 5296.3 | 1 | UniProt (P52292) Pfam (PF01749) | Homo sapiens (human) | Karyopherin subunit alpha-2,RAG cohort protein 1,SRP1-alpha |
Sequence modifications
A: 1 - 876 (UniProt: Q14974)
| PDB | External Database | Details |
|---|---|---|
| His 97 | Gln 97 | conflict |
| Arg 863 | Thr 863 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 102620.2 | |
| All* | Total formula weight | 102620.2 |
