9B3Z
Rat TRPV2 E724A/D725A bound to probenecid and 2-APB
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Transient receptor potential cation channel subfamily V member 2 | polymer | 761 | 86696.8 | 4 | UniProt (Q9WUD2) Pfam (PF12796) Pfam (PF00520) | Rattus norvegicus (Norway rat) | TrpV2,Osm-9-like TRP channel 2,OTRPC2,Stretch-activated channel 2B,Vanilloid receptor-like protein 1,VRL-1 |
| 2 | E, H, K, N (A, B, C, D) | 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE | non-polymer | 522.6 | 4 | Chemie (PEX) | |||
| 3 | F, I, L, O (A, B, C, D) | 2-aminoethyl diphenylborinate | non-polymer | 225.1 | 4 | Chemie (FZ4) | |||
| 4 | G, J, M, P (A, B, C, D) | 4-(dipropylsulfamoyl)benzoic acid | non-polymer | 285.4 | 4 | Chemie (RTO) |
Sequence modifications
A, B, C, D: 1 - 761 (UniProt: Q9WUD2)
| PDB | External Database | Details |
|---|---|---|
| Ala 724 | Glu 724 | engineered mutation |
| Ala 725 | Asp 725 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 346787.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 4132.3 | |
| All* | Total formula weight | 350919.7 |
