9B34

Structure of concanavalin A (ConA) dimer from the open-state structure of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to two ConA dimers. Type I interface between GluK2 ligand-binding domain and ConA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (E, F)	Concanavalin A	polymer	237	25622.4	2	UniProt (P02866) Pfam (PF00139)	Canavalia ensiformis (jack bean)	Con A
2	C, E (E, F)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	D, F (E, F)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)

Sequence modifications

E, F: 1 - 118 (UniProt: P02866)
E, F: 119 - 237 (UniProt: P02866)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	51244.8
Non-Polymers*	Number of molecules	4
	Total formula weight	211.0
All*	Total formula weight	51455.7

*Water molecules are not included.