9B28

Cryo-EM structure of the mouse TRPM3 alpha 2 channel in complex with primidone

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, C, B, D)	Transient receptor potential cation channel, subfamily M, member 3	polymer	1739	198674.3	4	UniProt (Q5F4S7) Pfam (PF18139) Pfam (PF25508) Pfam (PF00520) Pfam (PF16519) UniProt (by SIFTS) (J9SQF3)	Mus musculus (house mouse)
2	E, H, I, L, M... (A, C, B, D)	CHOLESTEROL HEMISUCCINATE	non-polymer		486.7	8	Chemie (Y01)
3	F, J, N, R (A, C, B, D)	[(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate	non-polymer		718.0	4	Chemie (6OU)
4	G, K, O, S (A, C, B, D)	primidone	non-polymer		218.3	4	Chemie (A1AIA)

Sequence modifications

A, C, B, D: 1 - 1709 (UniProt: Q5F4S7)

PDB	External Database	Details
Ser 1710	-	expression tag
Asn 1711	-	expression tag
Ser 1712	-	expression tag
Leu 1713	-	expression tag
Glu 1714	-	expression tag
Val 1715	-	expression tag
Leu 1716	-	expression tag
Phe 1717	-	expression tag
Gln 1718	-	expression tag
Gly 1719	-	expression tag
Pro 1720	-	expression tag
Asp 1721	-	expression tag
Tyr 1722	-	expression tag
Lys 1723	-	expression tag
Asp 1724	-	expression tag
Asp 1725	-	expression tag
Asp 1726	-	expression tag
Asp 1727	-	expression tag
Lys 1728	-	expression tag
Ala 1729	-	expression tag
His 1730	-	expression tag
His 1731	-	expression tag
His 1732	-	expression tag
His 1733	-	expression tag
His 1734	-	expression tag
His 1735	-	expression tag
His 1736	-	expression tag
His 1737	-	expression tag
His 1738	-	expression tag
His 1739	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	794697.2
Non-Polymers*	Number of molecules	16
	Total formula weight	7638.8
All*	Total formula weight	802336.0

*Water molecules are not included.