9B28
Cryo-EM structure of the mouse TRPM3 alpha 2 channel in complex with primidone
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, C, B, D) | Transient receptor potential cation channel, subfamily M, member 3 | polymer | 1739 | 198674.3 | 4 | UniProt (Q5F4S7) Pfam (PF18139) Pfam (PF25508) Pfam (PF00520) Pfam (PF16519) UniProt (by SIFTS) (J9SQF3) | Mus musculus (house mouse) | |
| 2 | E, H, I, L, M... (A, C, B, D) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 8 | Chemie (Y01) PubChem (16219150) PubChem (22210610) PubChem (65082) PubChem (45489984) PubChem (363416) PubChem (60078761) PubChem (500055) PubChem (73440805) PubChem (57163942) PubChem (89891013) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (99567469) PubChem (11969853) PubChem (137392566) PubChem (137496323) PubChem (124301053) PubChem (124302591) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (13301926) PubChem (13301927) PubChem (124914595) PubChem (124914596) PubChem (155804219) PubChem (169132514) PubChem (131705526) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028) | |||
| 3 | F, J, N, R (A, C, B, D) | [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | non-polymer | 718.0 | 4 | Chemie (6OU) PubChem (23727968) PubChem (3246975) PubChem (90470676) PubChem (5282290) PubChem (5283496) PubChem (123931) PubChem (5785226) PubChem (92863393) | |||
| 4 | G, K, O, S (A, C, B, D) | primidone | non-polymer | 218.3 | 4 | Chemie (A1AIA) PubChem (4909) |
Sequence modifications
A, C, B, D: 1 - 1709 (UniProt: Q5F4S7)
| PDB | External Database | Details |
|---|---|---|
| Ser 1710 | - | expression tag |
| Asn 1711 | - | expression tag |
| Ser 1712 | - | expression tag |
| Leu 1713 | - | expression tag |
| Glu 1714 | - | expression tag |
| Val 1715 | - | expression tag |
| Leu 1716 | - | expression tag |
| Phe 1717 | - | expression tag |
| Gln 1718 | - | expression tag |
| Gly 1719 | - | expression tag |
| Pro 1720 | - | expression tag |
| Asp 1721 | - | expression tag |
| Tyr 1722 | - | expression tag |
| Lys 1723 | - | expression tag |
| Asp 1724 | - | expression tag |
| Asp 1725 | - | expression tag |
| Asp 1726 | - | expression tag |
| Asp 1727 | - | expression tag |
| Lys 1728 | - | expression tag |
| Ala 1729 | - | expression tag |
| His 1730 | - | expression tag |
| His 1731 | - | expression tag |
| His 1732 | - | expression tag |
| His 1733 | - | expression tag |
| His 1734 | - | expression tag |
| His 1735 | - | expression tag |
| His 1736 | - | expression tag |
| His 1737 | - | expression tag |
| His 1738 | - | expression tag |
| His 1739 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 794697.2 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 7638.8 | |
| All* | Total formula weight | 802336.0 |
