9B04

Cryo-EM structure of human uMtCK1 in complex with ADP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Creatine kinase U-type, mitochondrial	polymer	418	47598.7	8	UniProt (P12532) Pfam (PF02807) Pfam (PF00217)	Homo sapiens (human)	Acidic-type mitochondrial creatine kinase,Mia-CK,Ubiquitous mitochondrial creatine kinase,U-MtCK
2	I, K, M, O, Q... (A, B, C, D, E...)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	8	Chemie (ADP)
3	J, L, N, P, R... (A, B, C, D, E...)	MAGNESIUM ION	non-polymer		24.3	8	Chemie (MG)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 379 (UniProt: P12532)

PDB	External Database	Details
Met -27	-	expression tag
Gly -26	-	expression tag
Ser -25	-	expression tag
Ser -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
Gly -15	-	expression tag
Leu -14	-	expression tag
Val -13	-	expression tag
Pro -12	-	expression tag
Arg -11	-	expression tag
Gly -10	-	expression tag
Ser -9	-	expression tag
His -8	-	expression tag
Met -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag
Gly 380	-	expression tag
Ser 381	-	expression tag
Ser 382	-	expression tag
Asp 383	-	expression tag
Tyr 384	-	expression tag
Lys 385	-	expression tag
Asp 386	-	expression tag
Asp 387	-	expression tag
Asp 388	-	expression tag
Asp 389	-	expression tag
Lys 390	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	380789.8
Non-Polymers*	Number of molecules	16
	Total formula weight	3612.0
All*	Total formula weight	384401.8

*Water molecules are not included.