9AZ3
Cryo-EM reveals molecular mechanisms underlying the inhibitory effect of netrin-4 on laminin matrix formation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | Laminin subunit gamma-1 | polymer | 305 | 34152.9 | 1 | UniProt (P11047) Pfam (PF00055) Pfam (PF00053) | Homo sapiens (human) | Laminin B2 chain,Laminin-1 subunit gamma,Laminin-10 subunit gamma,Laminin-11 subunit gamma,Laminin-2 subunit gamma,Laminin-3 subunit gamma,Laminin-4 subunit gamma,Laminin-6 subunit gamma,Laminin-7 subunit gamma,Laminin-8 subunit gamma,Laminin-9 subunit gamma,S-laminin subunit gamma,S-LAM gamma |
| 2 | B (N) | Netrin-4 | polymer | 284 | 32177.7 | 1 | UniProt (Q9JI33) Pfam (PF00055) Pfam (PF00053) | Mus musculus (house mouse) | Beta-netrin |
| 3 | C, D, E, F, G... (G, N) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) |
Sequence modifications
G: 37 - 341 (UniProt: P11047)
| PDB | External Database | Details |
|---|---|---|
| Trp 167 | Arg 167 | conflict |
| Ser 250 | Arg 250 | conflict |
| Arg 266 | Asp 266 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66330.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1548.5 | |
| All* | Total formula weight | 67879.1 |
