9AY1
Cryo-EM structure of SINV/EEEV in complex with a potently neutralizing human antibody IgG EEEV-373
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (1) | IgG EEEV-373 Heavy chain | polymer | 228 | 24386.2 | 1 | Homo sapiens (human) | ||
| 2 | B (2) | IgG EEEV-373 Light chain | polymer | 214 | 23296.9 | 1 | Homo sapiens (human) | ||
| 3 | C, D, E, F (A, B, C, D) | Spike glycoprotein E1 | polymer | 400 | 43628.0 | 4 | UniProt (Q4QXJ7) Pfam (PF01589) UniProt (by SIFTS) (W8R5E4) | Eastern equine encephalitis virus | E1 envelope glycoprotein |
| 4 | G, H, I, J (a, b, c, d) | E2 glycoprotein | polymer | 338 | 37921.1 | 4 | UniProt (A9XR09) Pfam (PF00943) UniProt (by SIFTS) (W8R5E4) | Eastern equine encephalitis virus | |
| 5 | K, L, M (E, F, G) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 6 | N (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 7 | O (D) | beta-D-mannopyranose | non-polymer | 180.2 | 1 | Chemie (BMA) | |||
| 8 | P, Q, R, S (a, b, c, d) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 373879.8 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2184.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1065.0 | |
| All* | Total formula weight | 377128.8 |
