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9AWY

Structure of full-length amyloidogenic immunoglobulin light chain H9 in complex with 3-(2-(4-(3-ethyl-3-phenylpyrrolidin-1-yl)-6-methyl-2-oxopyridin-1(2H)-yl)ethyl)-8-(imidazo[1,5-a]pyrazin-8-yl)-1,3,8-triazaspiro[4.5]decan-2-one

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
H9 Immunoglobulin Light Chainpolymer21622549.74Homo sapiens
2E, G, H, J, K
(A, B, C, D)
PHOSPHATE IONnon-polymer95.05Chemie (PO4)
3F, I
(A, C)
3-(2-{4-[(3R)-3-ethyl-3-phenylpyrrolidin-1-yl]-6-methyl-2-oxopyridin-1(2H)-yl}ethyl)-8-[(4R)-imidazo[1,5-a]pyrazin-8-yl]-1,3,8-triazaspiro[4.5]decan-2-onenon-polymer580.72Chemie (A1AH0)
4L, M, N, O
(A, B, C, D)
waterwater18.0884Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight90198.6
Non-Polymers*Number of molecules7
Total formula weight1636.3
All*Total formula weight91834.9
*Water molecules are not included.

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PDB entries from 2025-12-17

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