9AWE
The crystal structure of an engineered Protein GF with Human Kappa Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Fab Heavy Chain | polymer | 228 | 24177.9 | 1 | Homo sapiens | ||
| 2 | B (D) | Fab Light Chain | polymer | 215 | 23397.9 | 1 | Homo sapiens | ||
| 3 | C (A) | Histone chaperone ASF1 | polymer | 161 | 18244.4 | 1 | UniProt (P32447) Pfam (PF04729) | Homo sapiens (human) | Anti-silencing function protein 1,yASF1 |
| 4 | D (C) | Immunoglobulin G-binding protein G | polymer | 65 | 7090.8 | 1 | UniProt (P19909) Pfam (PF01378) | Streptococcus sp. 'group G' | IgG-binding protein G |
| 5 | E, F, G (B, D, C) | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
A: 2 - 159 (UniProt: P32447)
C: 2 - 64 (UniProt: P19909)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Leu 160 | - | expression tag |
| Glu 161 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Arg 15 | Lys 381 | conflict |
| Ser 18 | Lys 384 | conflict |
| Tyr 20 | Glu 386 | conflict |
| Thr 24 | Glu 390 | conflict |
| Phe 40 | Asn 406 | conflict |
| Gly 41 | Asp 407 | conflict |
| Lys 65 | - | expression tag |
| Leu 66 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 72911.1 | |
| All* | Total formula weight | 72911.1 |
