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9AUO

Structure of SARS-CoV-2 Mpro mutant (L50F,T304I)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
3C-like proteinase nsp5polymer30633871.62UniProt (P0DTD1)
Pfam (PF05409)
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase
2C
(A)
waterwater18.01Chemie (HOH)
Sequence modifications
A, B: 1 - 306 (UniProt: P0DTD1)
PDBExternal DatabaseDetails
Phe 50Leu 3313engineered mutation
Ile 304Thr 3567engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight67743.2
All*Total formula weight67743.2
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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