9ASX
BIFUNCTIONAL INHIBITION OF NEUTROPHIL ELASTASE AND CATHEPSIN G by Eap3 of S. aureus
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cathepsin-G | polymer | 223 | 25397.1 | 1 | UniProt (P08311) Pfam (PF00089) | Homo sapiens (human) | |
| 2 | B (B) | Neutrophil elastase | polymer | 218 | 23319.0 | 1 | UniProt (P08246) Pfam (PF00089) | Homo sapiens (human) | Bone marrow serine protease,Elastase-2,Human leukocyte elastase,HLE,Medullasin,PMN elastase |
| 3 | C (C) | Extracellular Adherence Protein | polymer | 100 | 11451.0 | 1 | UniProt (Q99QS1) Pfam (PF03642) | Staphylococcus aureus subsp. aureus Mu50 | Protein map |
| 4 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 5 | E (E) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 6 | F (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | G, H, I (A, B, C) | water | water | 18.0 | 205 | Chemie (HOH) |
Sequence modifications
C: 267 - 363 (UniProt: Q99QS1)
| PDB | External Database | Details |
|---|---|---|
| Gly 264 | - | expression tag |
| Ser 265 | - | expression tag |
| Thr 266 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 60167.1 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1303.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 61691.6 |
