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9ASQ

Human Drosha, DGCR8 and SRSF3 in complex with Pri-let-7f1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Isoform 4 of Droshapolymer1337155574.31UniProt (Q9NRR4)
Pfam (PF26050)
Pfam (PF14622)
Pfam (PF00636)
Pfam (PF00035)
Homo sapiens (human)Ribonuclease 3,Ribonuclease III,RNase III,p241
2B, C
(B, C)
Microprocessor complex subunit DGCR8polymer77386171.22UniProt (Q8WYQ5)
Pfam (PF00035)
Homo sapiens (human)DiGeorge syndrome critical region 8
3D
(E)
Pri-let-7f1polymer13743940.81GenBank (15212042)Homo sapiens (human)
4E
(H)
Serine/arginine-rich splicing factor 3polymer16419376.81UniProt (P84103)
Pfam (PF00076)
Homo sapiens (human)Pre-mRNA-splicing factor SRP20,Splicing factor,arginine/serine-rich 3
5F, G
(A)
ZINC IONnon-polymer65.42Chemie (ZN)
6H, I
(A)
CALCIUM IONnon-polymer40.12Chemie (CA)
7J
(E)
waterwater18.02Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight391234.3
Non-Polymers*Number of molecules4
Total formula weight211.0
All*Total formula weight391445.3
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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