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9ASO

Human Drosha and DGCR8 in complex with Pri-let-7a2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Isoform 4 of Droshapolymer1337155574.31UniProt (Q9NRR4)
Pfam (PF26050)
Pfam (PF14622)
Pfam (PF00636)
Pfam (PF00035)
Homo sapiens (human)Ribonuclease 3,Ribonuclease III,RNase III,p241
2B, C
(B, C)
Microprocessor complex subunit DGCR8polymer77386171.22UniProt (Q8WYQ5)
Pfam (PF00035)
Homo sapiens (human)DiGeorge syndrome critical region 8
3D
(E)
Pri-let-7a2polymer12740783.11GenBank (14189751)Homo sapiens (human)
4E, F
(A)
ZINC IONnon-polymer65.42Chemie (ZN)
5G, H
(A)
CALCIUM IONnon-polymer40.12Chemie (CA)
6I
(E)
waterwater18.02Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight368699.8
Non-Polymers*Number of molecules4
Total formula weight211.0
All*Total formula weight368910.8
*Water molecules are not included.

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PDB entries from 2026-01-21

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