9ARV

CryoEM structure of AMETA-A3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Isoform 1 of Immunoglobulin heavy constant mu	polymer	375	41152.3	10	UniProt (P01871) Pfam (PF07654)	Homo sapiens (human)	Ig mu chain C region,Ig mu chain C region BOT,Ig mu chain C region GAL,Ig mu chain C region OU, IgM Fc scaffold heavy chain
2	F (J)	Immunoglobulin J chain	polymer	167	19225.8	1	UniProt (P01591) Pfam (PF15097)	Homo sapiens (human)	Joining chain of multimeric IgA and IgM, IgM Fc scaffold J-chain
3	L, M, N, O, P (C, D, M, N, O)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)

Sequence modifications

A, B, C, D, E, L, M, N, O, P: 28 - 375 (UniProt: P01871)

PDB	External Database	Details
Gly 1	-	expression tag
Ser 2	-	expression tag
Arg 3	-	expression tag
Gly 4	-	expression tag
Val 5	-	expression tag
Pro 6	-	expression tag
His 7	-	expression tag
Ile 8	-	expression tag
Val 9	-	expression tag
Met 10	-	expression tag
Val 11	-	expression tag
Asp 12	-	expression tag
Ala 13	-	expression tag
Tyr 14	-	expression tag
Lys 15	-	expression tag
Arg 16	-	expression tag
Tyr 17	-	expression tag
Lys 18	-	expression tag
Gly 19	-	expression tag
Gly 20	-	expression tag
Gly 21	-	expression tag
Gly 22	-	expression tag
Ser 23	-	expression tag
Ile 24	-	expression tag
Asp 25	-	expression tag
Thr 26	-	expression tag
Thr 27	-	expression tag

J: 1 - 163 (UniProt: P01591)

PDB	External Database	Details
His 164	-	expression tag
His 165	-	expression tag
His 166	-	expression tag
His 167	-	expression tag
His 168	-	expression tag
His 169	-	expression tag
His 170	-	expression tag
His 171	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	11
	Total formula weight	430748.4
Non-Polymers*	Number of molecules	5
	Total formula weight	1106.0
All*	Total formula weight	431854.5

*Water molecules are not included.