9ARL
CryoEM structure of BoNT-NTNH-OrfX2 complex from Clostridium botulinum strain A1-ST7B, major class
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Botulinum neurotoxin type A | polymer | 1296 | 149479.9 | 1 | UniProt (P0DPI1) Pfam (PF01742) Pfam (PF07952) Pfam (PF07953) Pfam (PF07951) UniProt (by SIFTS) (P0DPI0) | Clostridium botulinum A str. Hall | BoNT/A,Bontoxilysin-A,BOTOX |
| 2 | B (B) | NtnH | polymer | 1161 | 135285.8 | 1 | UniProt (B0FNQ9) Pfam (PF01742) Pfam (PF22133) Pfam (PF07953) Pfam (PF08470) UniProt (by SIFTS) (C1FUH8) | Clostridium botulinum A | |
| 3 | C (C) | OrfX2 | polymer | 750 | 84823.3 | 1 | UniProt (B0FNQ5) Pfam (PF06597) UniProt (by SIFTS) (C1FUH4) | Clostridium botulinum A |
Sequence modifications
A: 1 - 1296 (UniProt: P0DPI1)
| PDB | External Database | Details |
|---|---|---|
| Gln 224 | Glu 224 | engineered mutation |
| Ala 363 | Arg 363 | engineered mutation |
| Phe 366 | Tyr 366 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 369588.9 | |
| All* | Total formula weight | 369588.9 |
