9ARF

Rat GluN1-GluN2B NMDA receptor channel in complex with glycine, glutamate, and EU-1622-A, in nonactive1 conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Glutamate receptor ionotropic, NMDA 1	polymer	847	95225.9	2	UniProt (P35439) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus (Norway rat)	GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1
2	B, D (B, D)	Glutamate receptor ionotropic, NMDA 2B	polymer	883	98888.9	2	UniProt (Q00960) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus (Norway rat)	GluN2B,Glutamate [NMDA] receptor subunit epsilon-2,N-methyl D-aspartate receptor subtype 2B,NMDAR2B,NR2B
3	E, F (E, F)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
4	G, J (A, C)	GLYCINE	non-polymer		75.1	2	Chemie (GLY)
5	H, K (B, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
6	I, L (B, D)	GLUTAMIC ACID	non-polymer		147.1	2	Chemie (GLU)

Sequence modifications

A, C: 1 - 847 (UniProt: P35439)

PDB	External Database	Details
Ser 22	Cys 22	conflict
Gln 61	Asn 61	conflict
Asp 239	Asn 239	conflict
Gln 350	Asn 350	conflict
Gln 471	Asn 471	conflict
Gln 491	Asn 491	conflict
Gln 771	Asn 771	conflict
Asn 844	Arg 844	conflict
Gly 845	Arg 845	conflict
Ala 846	Lys 846	conflict

B, D: 27 - 852 (UniProt: Q00960)

PDB	External Database	Details
Met -30	-	expression tag
Gly -29	-	expression tag
Thr -28	-	expression tag
Met -27	-	expression tag
Arg -26	-	expression tag
Leu -25	-	expression tag
Phe -24	-	expression tag
Leu -23	-	expression tag
Leu -22	-	expression tag
Ala -21	-	expression tag
Val -20	-	expression tag
Leu -19	-	expression tag
Phe -18	-	expression tag
Leu -17	-	expression tag
Phe -16	-	expression tag
Ser -15	-	expression tag
Phe -14	-	expression tag
Ala -13	-	expression tag
Arg -12	-	expression tag
Ala -11	-	expression tag
Thr -10	-	expression tag
Gly -9	-	expression tag
Trp -8	-	expression tag
Ser -7	-	expression tag
His -6	-	expression tag
Pro -5	-	expression tag
Gln -4	-	expression tag
Phe -3	-	expression tag
Glu -2	-	expression tag
Lys -1	-	expression tag
Gly 0	-	expression tag
Gly 1	-	expression tag
Gly 2	-	expression tag
Ser 3	-	expression tag
Gly 4	-	expression tag
Gly 5	-	expression tag
Gly 6	-	expression tag
Ser 7	-	expression tag
Gly 8	-	expression tag
Gly 9	-	expression tag
Ser 10	-	expression tag
Ala 11	-	expression tag
Trp 12	-	expression tag
Ser 13	-	expression tag
His 14	-	expression tag
Pro 15	-	expression tag
Gln 16	-	expression tag
Phe 17	-	expression tag
Glu 18	-	expression tag
Lys 19	-	expression tag
Gly 20	-	expression tag
Ala 21	-	expression tag
Leu 22	-	expression tag
Val 23	-	expression tag
Pro 24	-	expression tag
Arg 25	-	expression tag
Gly 26	-	expression tag
Ser 849	Cys 849	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	388229.7
Branched	Number of molecules	2
	Total formula weight	848.8
Non-Polymers*	Number of molecules	6
	Total formula weight	886.8
All*	Total formula weight	389965.3

*Water molecules are not included.