8ZYM

Complex structure of 60 Fab bound to DS2 prefusion F trimer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Fusion glycoprotein F0,Expression tag	polymer	558	61266.7	3	UniProt (C3UPB8)	Respiratory syncytial virus A2
2	D, E, F (D, E, F)	antibody light chain	polymer	112	12305.7	3		Mus musculus
3	G, H, I (G, H, I)	antidody heavy chain	polymer	121	13143.7	3		Mus musculus
4	J (B)	water	water		18.0	1	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 103 (UniProt: C3UPB8)

PDB	External Database	Details
Gly 46	Ser 46	engineered mutation
Asp 92	Glu 92	engineered mutation

A, B, C: 104 - 474 (UniProt: C3UPB8)

PDB	External Database	Details
Ser 105	Val 144	engineered mutation
Cys 110	Ala 149	engineered mutation
Cys 116	Ser 155	engineered mutation
Phe 151	Ser 190	engineered mutation
Leu 168	Val 207	engineered mutation
Pro 176	Ser 215	engineered mutation
Cys 251	Ser 290	engineered mutation
Arg 334	Leu 373	engineered mutation
Cys 419	Tyr 458	engineered mutation
Gln 426	Lys 465	engineered mutation

A, B, C: 475 - 558 (PDB: 8ZYM)

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	260148.0
All*	Total formula weight	260148.0

*Water molecules are not included.