8ZYE
Crystal structure of CD38 in complex with RP02 antibody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | polymer | 242 | 28182.0 | 1 | UniProt (P28907) Pfam (PF02267) | Homo sapiens (human) | CD38,2'-phospho-ADP-ribosyl cyclase,2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase,2'-phospho-cyclic-ADP-ribose transferase,ADP-ribosyl cyclase 1,ADPRC 1,Cyclic ADP-ribose hydrolase 1,cADPR hydrolase 1,T10 |
| 2 | B (B) | RP02 scFv | polymer | 226 | 23958.6 | 1 | Homo sapiens | ||
| 3 | C (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 4 | D, E, J (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | F, G, H, I, K... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 6 | N, O (A, B) | water | water | 18.0 | 47 | Chemie (HOH) |
Sequence modifications
A: 45 - 286 (UniProt: P28907)
| PDB | External Database | Details |
|---|---|---|
| Asp 100 | Asn 100 | conflict |
| Ala 164 | Asn 164 | conflict |
| Asp 209 | Asn 209 | conflict |
| Asp 219 | Asn 219 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52140.6 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 828.8 | |
| All* | Total formula weight | 52969.4 |
