8ZY7

Sarbecovirus HeB2013 Spike Trimer in a Locked Conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Spike glycoprotein	polymer	1255	138951.8	3	UniProt (A0A0U1WHK9) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) UniProt (by SIFTS) (A0A0U1WHH0)	BtRf-BetaCoV/HeB2013
2	D, E, F, G, H... (D, E, F, G, H...)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	18	In PDB GlyTouCan (G42666HT)
3	AA, AB, BA, BB, CA... (A, C, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	33	Chemie (NAG)

Sequence modifications

A, B, C: 1 - 1176 (UniProt: A0A0U1WHK9)

PDB	External Database	Details
Ile 29	Thr 29	conflict
Pro 612	Ser 612	conflict
Phe 1069	Ser 1069	conflict
Gly 1177	-	expression tag
Ser 1178	-	expression tag
Gly 1179	-	expression tag
Tyr 1180	-	expression tag
Ile 1181	-	expression tag
Pro 1182	-	expression tag
Glu 1183	-	expression tag
Ala 1184	-	expression tag
Pro 1185	-	expression tag
Arg 1186	-	expression tag
Asp 1187	-	expression tag
Gly 1188	-	expression tag
Gln 1189	-	expression tag
Ala 1190	-	expression tag
Tyr 1191	-	expression tag
Val 1192	-	expression tag
Arg 1193	-	expression tag
Lys 1194	-	expression tag
Asp 1195	-	expression tag
Gly 1196	-	expression tag
Glu 1197	-	expression tag
Trp 1198	-	expression tag
Val 1199	-	expression tag
Leu 1200	-	expression tag
Leu 1201	-	expression tag
Ser 1202	-	expression tag
Thr 1203	-	expression tag
Phe 1204	-	expression tag
Leu 1205	-	expression tag
Leu 1206	-	expression tag
Glu 1207	-	expression tag
Val 1208	-	expression tag
Leu 1209	-	expression tag
Phe 1210	-	expression tag
Gln 1211	-	expression tag
Gly 1212	-	expression tag
Pro 1213	-	expression tag
Gly 1214	-	expression tag
His 1215	-	expression tag
His 1216	-	expression tag
His 1217	-	expression tag
His 1218	-	expression tag
His 1219	-	expression tag
His 1220	-	expression tag
His 1221	-	expression tag
His 1222	-	expression tag
Ser 1223	-	expression tag
Ala 1224	-	expression tag
Trp 1225	-	expression tag
Ser 1226	-	expression tag
His 1227	-	expression tag
Pro 1228	-	expression tag
Gln 1229	-	expression tag
Phe 1230	-	expression tag
Glu 1231	-	expression tag
Lys 1232	-	expression tag
Gly 1233	-	expression tag
Gly 1234	-	expression tag
Gly 1235	-	expression tag
Ser 1236	-	expression tag
Gly 1237	-	expression tag
Gly 1238	-	expression tag
Gly 1239	-	expression tag
Gly 1240	-	expression tag
Ser 1241	-	expression tag
Gly 1242	-	expression tag
Gly 1243	-	expression tag
Ser 1244	-	expression tag
Ala 1245	-	expression tag
Trp 1246	-	expression tag
Ser 1247	-	expression tag
His 1248	-	expression tag
Pro 1249	-	expression tag
Gln 1250	-	expression tag
Phe 1251	-	expression tag
Glu 1252	-	expression tag
Lys 1253	-	expression tag
Ser 1254	-	expression tag
Ala 1255	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	416855.4
Branched	Number of molecules	18
	Total formula weight	7639.2
Non-Polymers*	Number of molecules	33
	Total formula weight	7299.9
All*	Total formula weight	431794.5

*Water molecules are not included.