8ZX4

LPI-bound GPR55 in complex with G13

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	engineered miniGalpha 13	polymer	230	26574.4	1	Pfam (PF00503) UniProt (by SIFTS) (Q14344)	Homo sapiens
2	B (B)	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	polymer	345	37915.5	1	UniProt (P62873) Pfam (PF00400)	Homo sapiens (human)	Transducin beta chain 1
3	C (G)	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2	polymer	71	7861.1	1	UniProt (P59768) Pfam (PF00631)	Homo sapiens (human)	G gamma-I
4	D (R)	G-protein coupled receptor 55	polymer	297	34162.5	1	UniProt (Q9Y2T6) Pfam (PF00001)	Homo sapiens (human)
5	E (R)	[(2~{R})-2-oxidanyl-3-[oxidanyl-[(2~{S},3~{R},5~{R},6~{R})-2,3,4,5,6-pentakis(oxidanyl)cyclohexyl]oxy-phosphoryl]oxy-propyl] hexadecanoate	non-polymer		572.6	1	Chemie (A1D9E)

Sequence modifications

B: 2 - 340 (UniProt: P62873)

PDB	External Database	Details
Met -4	-	initiating methionine
Gly -3	-	expression tag
Ser -2	-	expression tag
Leu -1	-	expression tag
Leu 0	-	expression tag
Gln 1	-	expression tag

R: 1 - 297 (UniProt: Q9Y2T6)

PDB	External Database	Details
Val 287	Cys 287	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	106513.6
Non-Polymers*	Number of molecules	1
	Total formula weight	572.6
All*	Total formula weight	107086.2

*Water molecules are not included.