8ZWO

Structure of CTF18-PCNA with ATP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Chromosome transmission fidelity protein 18 homolog	polymer	1012	111407.1	1	UniProt (Q8WVB6) Pfam (PF00004)	Homo sapiens (human)	hCTF18,CHL12
2	B (B)	Replication factor C subunit 2	polymer	354	39203.2	1	UniProt (P35250) Pfam (PF00004) Pfam (PF08542)	Homo sapiens (human)	Activator 1 40 kDa subunit,A1 40 kDa subunit,Activator 1 subunit 2,Replication factor C 40 kDa subunit,RF-C 40 kDa subunit,RFC40
3	C (C)	Replication factor C subunit 5	polymer	340	38545.5	1	UniProt (P40937) Pfam (PF00004) Pfam (PF21960) Pfam (PF08542)	Homo sapiens (human)	Activator 1 36 kDa subunit,A1 36 kDa subunit,Activator 1 subunit 5,Replication factor C 36 kDa subunit,RF-C 36 kDa subunit,RFC36
4	D (D)	Replication factor C subunit 4	polymer	363	39735.7	1	UniProt (P35249) Pfam (PF00004) Pfam (PF21960) Pfam (PF08542)	Homo sapiens (human)	Activator 1 37 kDa subunit,A1 37 kDa subunit,Activator 1 subunit 4,Replication factor C 37 kDa subunit,RF-C 37 kDa subunit,RFC37
5	E (E)	Replication factor C subunit 3	polymer	362	41436.3	1	UniProt (P40938) Pfam (PF13177) Pfam (PF21960) Pfam (PF22534)	Homo sapiens (human)	Activator 1 38 kDa subunit,A1 38 kDa subunit,Activator 1 subunit 3,Replication factor C 38 kDa subunit,RF-C 38 kDa subunit,RFC38
6	F, G, H (F, G, H)	Proliferating cell nuclear antigen	polymer	267	29617.7	3	UniProt (P12004) Pfam (PF00705) Pfam (PF02747)	Homo sapiens (human)	PCNA,Cyclin
7	I, J, K (A, B, C)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	3	Chemie (ATP)
8	L (E)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)

Sequence modifications

A: 2 - 975 (UniProt: Q8WVB6)

PDB	External Database	Details
Met -36	-	initiating methionine
Ser -35	-	expression tag
Ala -34	-	expression tag
Trp -33	-	expression tag
Ser -32	-	expression tag
His -31	-	expression tag
Pro -30	-	expression tag
Gln -29	-	expression tag
Phe -28	-	expression tag
Glu -27	-	expression tag
Lys -26	-	expression tag
Gly -25	-	expression tag
Gly -24	-	expression tag
Gly -23	-	expression tag
Ser -22	-	expression tag
Gly -21	-	expression tag
Gly -20	-	expression tag
Gly -19	-	expression tag
Ser -18	-	expression tag
Gly -17	-	expression tag
Gly -16	-	expression tag
Ser -15	-	expression tag
Ala -14	-	expression tag
Trp -13	-	expression tag
Ser -12	-	expression tag
His -11	-	expression tag
Pro -10	-	expression tag
Gln -9	-	expression tag
Phe -8	-	expression tag
Glu -7	-	expression tag
Lys -6	-	expression tag
Glu -5	-	expression tag
Asn -4	-	expression tag
Leu -3	-	expression tag
Tyr -2	-	expression tag
Phe -1	-	expression tag
Gln 0	-	expression tag
Gly 1	-	expression tag

E: 1 - 356 (UniProt: P40938)

PDB	External Database	Details
Met -5	-	initiating methionine
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

F, G, H: 1 - 261 (UniProt: P12004)

PDB	External Database	Details
Met -5	-	initiating methionine
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	359180.8
Non-Polymers*	Number of molecules	4
	Total formula weight	1948.7
All*	Total formula weight	361129.5

*Water molecules are not included.