8ZWC

Cryo-EM Structure of the BLOC-3 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	BLOC-3 complex member HPS1	polymer	700	79376.7	1	UniProt (Q92902) Pfam (PF19036) Pfam (PF19037) Pfam (PF19038)	Homo sapiens (human)	Hermansky-Pudlak syndrome 1 protein
2	B (B)	BLOC-3 complex member HPS4	polymer	480	52840.0	1	UniProt (Q9NQG7) Pfam (PF19031) Pfam (PF19033)	Homo sapiens (human)	Hermansky-Pudlak syndrome 4 protein,Light-ear protein homolog

Sequence modifications

B: 1 - 708 (UniProt: Q9NQG7)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag
-	Ser 289	deletion
-	Thr 290	deletion
-	Ser 291	deletion
-	Ala 292	deletion
-	Leu 293	deletion
-	Lys 294	deletion
-	Glu 295	deletion
-	Asn 296	deletion
-	Ala 297	deletion
-	Thr 298	deletion
-	Gly 299	deletion
-	His 300	deletion
-	Val 301	deletion
-	Glu 302	deletion
-	Ser 303	deletion
-	Met 304	deletion
-	Ala 305	deletion
-	Trp 306	deletion
-	Thr 307	deletion
-	Thr 308	deletion
-	Pro 309	deletion
-	Asp 310	deletion
-	Pro 311	deletion
-	Thr 312	deletion
-	Ser 313	deletion
-	Pro 314	deletion
-	Asp 315	deletion
-	Glu 316	deletion
-	Ala 317	deletion
-	Cys 318	deletion
-	Pro 319	deletion
-	Asp 320	deletion
-	Gly 321	deletion
-	Arg 322	deletion
-	Lys 323	deletion
-	Glu 324	deletion
-	Asn 325	deletion
-	Gly 326	deletion
-	Cys 327	deletion
-	Leu 328	deletion
-	Ser 329	deletion
-	Gly 330	deletion
-	His 331	deletion
-	Asp 332	deletion
-	Leu 333	deletion
-	Glu 334	deletion
-	Ser 335	deletion
-	Ile 336	deletion
-	Arg 337	deletion
-	Pro 338	deletion
-	Ala 339	deletion
-	Gly 340	deletion
-	Leu 341	deletion
-	His 342	deletion
-	Asn 343	deletion
-	Ser 344	deletion
-	Ala 345	deletion
-	Arg 346	deletion
-	Gly 347	deletion
-	Glu 348	deletion
-	Val 349	deletion
-	Leu 350	deletion
-	Gly 351	deletion
-	Leu 352	deletion
-	Ser 353	deletion
-	Ser 354	deletion
-	Ser 355	deletion
-	Leu 356	deletion
-	Gly 357	deletion
-	Lys 358	deletion
-	Glu 359	deletion
-	Leu 360	deletion
-	Val 361	deletion
-	Phe 362	deletion
-	Leu 363	deletion
-	Gln 364	deletion
-	Glu 365	deletion
-	Glu 366	deletion
-	Leu 367	deletion
-	Asp 368	deletion
-	Leu 369	deletion
-	Ser 370	deletion
-	Glu 371	deletion
-	Ile 372	deletion
-	His 373	deletion
-	Ile 374	deletion
-	Pro 375	deletion
-	Glu 376	deletion
-	Ala 377	deletion
-	Gln 378	deletion
-	Glu 379	deletion
-	Val 380	deletion
-	Glu 381	deletion
-	Met 382	deletion
-	Ala 383	deletion
-	Ser 384	deletion
-	Gly 385	deletion
-	His 386	deletion
-	Phe 387	deletion
-	Ala 388	deletion
-	Phe 389	deletion
-	Leu 390	deletion
-	His 391	deletion
-	Val 392	deletion
-	Pro 393	deletion
-	Val 394	deletion
-	Pro 395	deletion
-	Asp 396	deletion
-	Gly 397	deletion
-	Arg 398	deletion
-	Ala 399	deletion
-	Pro 400	deletion
-	Tyr 401	deletion
-	Cys 402	deletion
-	Lys 403	deletion
-	Ala 404	deletion
-	Ser 405	deletion
-	Leu 406	deletion
-	Ser 407	deletion
-	Ala 408	deletion
-	Ser 409	deletion
-	Ser 410	deletion
-	Ser 411	deletion
-	Leu 412	deletion
-	Glu 413	deletion
-	Pro 414	deletion
-	Thr 415	deletion
-	Pro 416	deletion
-	Pro 417	deletion
-	Glu 418	deletion
-	Asp 419	deletion
-	Thr 420	deletion
-	Ala 421	deletion
-	Ile 422	deletion
-	Ser 423	deletion
-	Ser 424	deletion
-	Leu 425	deletion
-	Arg 426	deletion
-	Pro 427	deletion
-	Pro 428	deletion
-	Ser 429	deletion
-	Ala 430	deletion
-	Pro 431	deletion
-	Glu 432	deletion
-	Met 433	deletion
-	Leu 434	deletion
-	Thr 435	deletion
-	Gln 436	deletion
-	His 437	deletion
-	Gly 438	deletion
-	Ala 439	deletion
-	Gln 440	deletion
-	Glu 441	deletion
-	Gln 442	deletion
-	Leu 443	deletion
-	Glu 444	deletion
-	Asp 445	deletion
-	His 446	deletion
-	Pro 447	deletion
-	Gly 448	deletion
-	His 449	deletion
-	Ser 450	deletion
-	Ser 451	deletion
-	Gln 452	deletion
-	Ala 453	deletion
-	Pro 454	deletion
-	Ile 455	deletion
-	Pro 456	deletion
-	Arg 457	deletion
-	Ala 458	deletion
-	Asp 459	deletion
-	Pro 460	deletion
-	Leu 461	deletion
-	Pro 462	deletion
-	Arg 463	deletion
-	Arg 464	deletion
-	Thr 465	deletion
-	Arg 466	deletion
-	Arg 467	deletion
-	Pro 468	deletion
-	Leu 469	deletion
-	Leu 470	deletion
-	Leu 471	deletion
-	Pro 472	deletion
-	Arg 473	deletion
-	Leu 474	deletion
-	Asp 475	deletion
-	Pro 476	deletion
-	Gly 477	deletion
-	Gln 478	deletion
-	Arg 479	deletion
-	Gly 480	deletion
-	Asn 481	deletion
-	Lys 482	deletion
-	Leu 483	deletion
-	Pro 484	deletion
-	Thr 485	deletion
-	Gly 486	deletion
-	Glu 487	deletion
-	Gln 488	deletion
-	Gly 489	deletion
-	Leu 490	deletion
-	Asp 491	deletion
-	Glu 492	deletion
-	Asp 493	deletion
-	Val 494	deletion
-	Asp 495	deletion
-	Gly 496	deletion
-	Val 497	deletion
-	Cys 498	deletion
-	Glu 499	deletion
-	Ser 500	deletion
-	His 501	deletion
-	Ala 502	deletion
-	Ala 503	deletion
-	Pro 504	deletion
-	Gly 505	deletion
-	Leu 506	deletion
-	Glu 507	deletion
-	Cys 508	deletion
-	Ser 509	deletion
-	Ser 510	deletion
-	Gly 511	deletion
-	Ser 512	deletion
-	Ala 513	deletion
-	Asn 514	deletion
-	Cys 515	deletion
-	Gln 516	deletion
-	Gly 517	deletion
-	Ala 518	deletion

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	132216.7
All*	Total formula weight	132216.7

*Water molecules are not included.