8ZTB
Crystal Structure of Active Site Influencing Variant (F218Y) of Imp-1 Metallo-beta-lactamase.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Metallo-beta-lactamase type 2 | polymer | 220 | 24350.8 | 2 | UniProt (P52699) Pfam (PF00753) | Serratia marcescens | B2 metallo-beta-lactamase,BLA-IMP,IMP-1,Beta-lactamase type II,Metallo-beta-lactamase type II |
| 2 | C, D (B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 3 | E, F, N, O (B, A) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | G (B) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | H, I, J, K (B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 6 | L, M (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 7 | P, Q (A) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 8 | R (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 9 | S, T (B, A) | water | water | 18.0 | 25 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 220 (UniProt: P52699)
| PDB | External Database | Details |
|---|---|---|
| Tyr 154 | Phe 173 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48701.5 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1042.8 | |
| All* | Total formula weight | 49744.3 |
