8ZT1

sStructure of calcium preference ATP-gated channel P2X1 in complex with BTFA

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	P2X purinoceptor 1	polymer	428	48544.7	3	UniProt (P51576) Pfam (PF00864)	Mus musculus (house mouse)	P2X1,ATP receptor,Purinergic receptor
2	D, E, F, K, L... (A, B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	7	Chemie (NAG)
3	G (A)	3,5-bis(trifluoromethyl)aniline	non-polymer		229.1	1	Chemie (A1D8Z)
4	H, N, Q (A, B, C)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	3	Chemie (ATP)
5	I, O (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
6	J, P, S (A, B, C)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
7	T, U, V (A, B, C)	water	water		18.0	4	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 399 (UniProt: P51576)

PDB	External Database	Details
Met 0	-	initiating methionine
Lys 400	-	expression tag
Leu 401	-	expression tag
Leu 402	-	expression tag
Glu 403	-	expression tag
Val 404	-	expression tag
Leu 405	-	expression tag
Phe 406	-	expression tag
Gln 407	-	expression tag
Gly 408	-	expression tag
Pro 409	-	expression tag
His 410	-	expression tag
His 411	-	expression tag
His 412	-	expression tag
His 413	-	expression tag
His 414	-	expression tag
His 415	-	expression tag
His 416	-	expression tag
His 417	-	expression tag
His 418	-	expression tag
His 419	-	expression tag
Asp 420	-	expression tag
Tyr 421	-	expression tag
Lys 422	-	expression tag
Asp 423	-	expression tag
Asp 424	-	expression tag
Asp 425	-	expression tag
Asp 426	-	expression tag
Lys 427	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	145634.0
Non-Polymers*	Number of molecules	16
	Total formula weight	3452.2
All*	Total formula weight	149086.2

*Water molecules are not included.